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Since the most common risk factor for developing NAFLD is obesity, clinical management primarily emphasizes weight loss, which can be achieved through diet modification, exercise, and surgical interventions.
Bariatric surgery, including laparoscopic sleeve gastrectomy LSG , has been shown to be more effective for resolution of metabolic diseases than intensive medical treatment alone. Noninvasive examinations for NAFLD exist, but histological examination remains the gold standard for diagnosis and staging of the disease. We gathered data from 57 patients who had CTs before and after surgery for the study. We followed the ethical principles stated in the guidelines of the World Medical Association's Declaration of Helsinki in this study.
This study was approved by the ethics committee of Oita University Faculty of Medicine. The surgical techniques for the LSG procedures have been previously published. The stump of the stomach is then buttressed by interrupted sutures. In the liver, we located four ROIs at each segment right anterior, right posterior, left medial and left lateral. The four measurements in each segment of the liver and spleen were averaged. Furthermore, the remission rates of comorbidities were not statistically different between the groups.
We also found no significant differences in preoperative rates of comorbidities between the two groups. In addition, the preoperative liver enzymes and metabolic parameters were not significantly different between the two groups.
A Cochrane review also showed a significant improvement for patients with NAFLD following bariatric surgery, demonstrating that surgical intervention for obesity reduces its associated comorbidities. Steatosis can be graded as follows: Comparing our data with those data, the ALT levels in our patients were lower. Therefore, we think the differences in results are probably related to the differing patient populations. In our study, we analyzed liver volumes before and after LSG.